Solubility of aceclofenac in polyamidoamine dendrimer solutions
نویسندگان
چکیده
منابع مشابه
Using Generation 3 Polyamidoamine Dendrimer as Adsorbent for the Removal of Pentavalent Arsenic from Aqueous Solutions
Introduction: Arsenic is known as a carcinogenic compound in drinking water. It can cause acute and chronic effects on human health. In this study, the effect of polyamidoamine dendrimer generation 3 (PAMAM G3) as adsorbents for removal of arsenic (V) from aqueous solutions was evaluated. Materials and Methods: Adsorption experiment was studied in batch system and the effect of different varia...
متن کاملPolyamidoamine dendrimer impairs mitochondrial oxidation in brain tissue
BACKGROUND The potential nanocarrier polyamidoamine (PAMAM) generation 5 (G5-NH(2)) dendrimer has been shown to evoke lasting neuronal depolarization and cell death in a concentration-dependent manner. In this study we explored the early progression of G5-NH(2) action in brain tissue on neuronal and astroglial cells. RESULTS In order to describe early mechanisms of G5-NH(2) dendrimer action i...
متن کاملSynthesis, cellular transport, and activity of polyamidoamine dendrimer-methylprednisolone conjugates.
Dendrimers have emerged as promising multifunctional nanomaterials for drug delivery due to their well-defined size and tailorability. We compare two schemes to obtain methylprednisolone (MP)-polyamidoamine dendrimer (PAMAM-G4-OH) conjugate. Glutaric acid (GA) was used as a spacer to facilitate the conjugation. In scheme A, PAMAM-G4-OH was first coupled to GA and then further conjugated with MP...
متن کاملSolubility and Permeability Studies of Aceclofenac in Different Oils
Purpose: To measure the extent of solubility of the lipophilic drug, aceclofenac, in 13 oils as well as its in vitro permeability from these oils in order to develop optimized topical microemulsion and microemulsion-based gel for improved bioavailability. Methods: UV spectrophotometeric method was used at the wavelength of 276 nm to measure the dissolved quantity of aceclofenac in each of the o...
متن کاملusing generation 3 polyamidoamine dendrimer (pamam g3)as adsorbent for the removal of pentavalent arsenic fromaqueous solutions
introduction: arsenic is known as a carcinogenic compound in drinking water . it can cause acute and chronic effects on human health. in this study, the effect of polyamidoamine dendrimer generation 3(pamam g3) as adsorbents for removal of arsenic (v) from aqueous solutions was evaluated. methods: adsorption experiment was studied in batch system and the effect of different variables like p...
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutical Investigation
سال: 2011
ISSN: 2230-973X
DOI: 10.4103/2230-973x.85962